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Lots of receptor-mediated situations present the phenomenon of desensitization, meaning that continued or recurring administration of the drug provides a progressively lesser effect. Among the complex mechanisms associated are conversion in the receptors into a refractory (unresponsive) point out while in the existence of the agonist, making sure that activation https://z-i-e19864.techionblog.com/27810768/manual-article-review-is-required-for-this-article

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