Remark: Barbiturates could maximize adverse effects, like respiratory depression, made by toxic doses of TCAs. With therapeutic doses of TCAs, barbiturates improve metabolism and decrease blood concentrations of TCAs. pentobarbital will minimize the level or outcome of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Coadministration of ... https://brettb221six8.blogsvirals.com/profile