Abstract ISG15. an interferon-stimulated ubiquitin-like protein. plays a multifaceted role in tumorigenesis and immune regulation. This study comprehensively evaluates ISG15 as a prognostic biomarker and predictor of immunotherapy response through pan-cancer bioinformatics analysis and experimental validation. https://www.jmannino.com/great-pick-Sophie-Allport-Zebra-Made-to-Measure-Blackout-Roller-Blind-Soft-Grey-Blue-top-super/